NFL – FREE PLAY: Falcons (473) vs. 49ers (474)

Atlanta Falcons vs. San Francisco 49ers: Game Preview and Analysis

Game Details

Date: Sunday, October 19, 2025

Time: 8:20 PM EDT

Broadcast: NBC (Sunday Night Football)

Venue: Levi’s Stadium, Santa Clara, CA

Team Records

Atlanta Falcons

Straight Up (SU): 3-2

Against the Spread (ATS): 3-2

ATS Road: 1-1

San Francisco 49ers

Straight Up (SU): 4-2

Against the Spread (ATS): 3-3

ATS Home: 0-2

Team Analysis

San Francisco 49ers

The 49ers return home after a two game road trip, where they competed closely in Tampa Bay but ultimately fell short. The team may see a boost with key players potentially returning from injury, including wide receivers Jauan Jennings and Ricky Pearsall. If Pearsall plays, his player props could offer value due to a favorable matchup against Atlanta’s secondary.

However, quarterback Brock Purdy is not expected to play, leaving Mac Jones to lead the offense. Despite the quarterback uncertainty, San Francisco’s passing attack remains one of the league’s stronger units, bolstered by Christian McCaffrey’s dynamic presence in the backfield. Tight end Jake Tonges has emerged as a red zone target and could be a sneaky play for an anytime touchdown (ATTD) prop.

At home, the 49ers have struggled against the spread (0-2 ATS), which raises concerns about their ability to cover as favorites.

Atlanta Falcons

Coming off an impressive Monday Night Football win against the Buffalo Bills, the Falcons are riding high and don’t appear to be in a letdown spot. Their offense has shown recent improvement, scoring 34 and 24 points in their last two games overall. However, their road offense has been inconsistent, averaging just 11 points per game and posting a shutout in their last road game against Carolina.

Atlanta’s game plan will likely center on running back Bijan Robinson to control the ground game, but their passing attack could find success against a 49ers defense that has shown vulnerabilities. The Falcons’ defense has also been a pleasant surprise, and their recent offensive output suggests they may have found a rhythm.

The betting line has been moving in Atlanta’s favor, reflecting growing confidence in their ability to compete in this matchup.

Key Matchup Insights

Both teams rank as average on offense and defense, setting the stage for a competitive game.

San Francisco’s passing offense remains a strength, even with a backup quarterback Mac Jones, while Atlanta’s improving defense could challenge them.

Atlanta’s run heavy approach with Bijan Robinson should keep the 49ers’ defense honest, potentially opening up opportunities in the passing game.

Player prop considerations:

Ricky Pearsall (if active): Look for receiving yards or receptions props due to a favorable matchup.

Jake Tonges: A potential value pick for an anytime touchdown, given his recent red zone involvement.

Betting Recommendation

The Falcons’ recent offensive surge and improving defense make them an attractive underdog in this spot. Their ability to exploit San Francisco’s home ATS struggles and the uncertainty at quarterback for the 49ers tilts the value in their favor.

Pick: Falcons +2.5, Moneyline +114

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