Featured Game: Illinois Illini (-3/49.5) vs. Duke Blue Devils
Time: 12:00 pm ET / 9:00 am PT
Television: ESPN
After a dominating victory to open the 2025 season last week, the Fighting Illini travel to Tobacco Country as Illinois battles the Duke Blue Devils on Saturday afternoon. Illinois crushed Western Illinois at home in a 52-3 rout while Duke won their first game of the year last Saturday, beating FCS club Elon 38-3. New transfer QB Darian Mensah threw for 389 yards and 3 TDs in the win, with the former Tulane player going a perfect 11-for-11 on passes in the second half.
Illinois was picked by many to possibly sneak into the College Football Playoff this year because of their depth of experienced players, but historically, the Illini has struggled to play well against non-conference opponents on the road, failing to cover in eight straight situations. Take the points with the home dog here, and sprinkle a bit on the moneyline as well with the Blue Devils.
Pick: Duke Blue Devils +3 -110
