Bryce Young and the Carolina Panthers struggled significantly in their last outing, with the offensive line failing to provide adequate protection, leading to a disjointed offensive performance. Defensively, Carolina was unable to contain the run, exposing a critical vulnerability. In contrast, Kyler Murray and the Arizona Cardinals showcased a strong performance last week, particularly at home, where Murray tends to excel. The Cardinals’ robust rushing attack is poised to exploit Carolina’s defensive weaknesses against the run, likely creating significant problems for the Panthers. Carolina’s defense also lacks an effective pass rush, which should give Murray ample time in the pocket to make plays. Meanwhile, Young has consistently struggled in road games, and there’s little indication of a turnaround this week. Arizona has a strong recent trend, going 6-1 against the spread (ATS) in their last seven games against NFC South opponents and covering in their last three home openers. The Cardinals are well-positioned to build on their momentum at home, while the Panthers are likely to continue their road struggles. Given these factors, Arizona is the clear choice to cover the spread. Pick: Cardinals -6.5

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